Table 1 Molecular characterization of the 87 EGFR ex20ins mutations
Subtypes | Number of each subtype | Mutation frequency of each subtype |
|---|---|---|
p.A767_V769dup | 25 | 28.74% |
p.S768_D770dup | 11 | 12.64% |
p.N771_P772insH; p.A763_Y764insFQEA | 4 | 4.60% |
p.A767_S768insSVD; p.D770_N771insG; p.D770_N771insSVD; p.H773dup; p.N771delinsKT; p.M766_A767insASV; p.P772_H773insHA; p.772_H773insTNP; p.S768_V769delinsIL; | 2 | 2.30% |
p.N771_P772delinsGGT; p.D770_N771insY; p.D770_P772dup; p.D770delinsGNPH; p.D770delinsGY; p.H773_V774delinsLM; p.H773_V774dup; p.N771_H773dup; p.N771_P772insG; p.N771_P772insT; p.N771_P772insV; p.N771delinsKH; p.N771delinsRH; p.N771dup; p.P772_H773dup; p.P772_H773insGNNP; p.P772_H773insGNP; p.P772_H773insHT; p.S768_V769insVAS; p.V769_D770insASV; p.V769_D770insG; p.V769_D770insGSV; p.V769_D770insGTR; p.V769_D770insSSV; p.M766delinsMASV | 1 | 1.15% |