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Table 3 Univariable and multivariable analyses to identify predictors of disease free survival in HCC patients treated by resection

From: Platelet-albumin-bilirubin versus albumin–bilirubin as a predictor of long-term survival for hepatitis B-Induced hepatocellular carcinoma after hepatic resection

Univariable

Multivariable

 

ALBI model

PALBI model

 

HR

95% CI

P

HR

95% CI

P

HR

95% CI

P

Male

1.022

0.802-1.303

0.859

      

Age (≥60 years)

1.038

0.813-1.324

0.766

      

PALBI grade

1.145

1.023-1.310

0.041

   

1.140

0.994-1.307

0.060

ALBI grade

1.081

0.897-1.302

0.414

      

Liver cirrhosis

1.165

0.929-1.461

0.186

      

AFP≥400 ng/mL

1.660

1.408-1.958

<0.001

   

1.479

1.245-1.756

<0.001

Edmonson grade III–IV

1.325

0.843-1.856

0.352

      

Child-Pugh B class

0.895

0.606-1.323

0.579

      

Tumor number

1.910

1.611-2.263

<0.001

   

1.586

1.300-1.890

<0.001

Tumor size≥5 cm

2.022

1.690-2.419

<0.001

   

1.289

1.048-1.585

0.016

Tumor capsule

1.656

1.398-1.961

<0.001

   

1.225

1.023-1.467

0.027

Albumin≥35 g/L

0.983

0.725-1.333

0.912

      

Plateletcount≥100 × 109/L

1.439

1.108-1.869

0.006

      

AST≥80U/L

1.306

0.856-1.625

0.417

      

ALT≥80U/L

0.962

0.746-1.241

0.768

      

Total bilirubin

≥17.1μmol/L

0.957

0.797-1.151

0.643

      
  1. Abbreviations: HBsAg, hepatitis B surface antigen; AFP, alpha-fetoprotein; BCLC, Barcelona Clinic Liver Cancer; AST, aspartate aminotransferase; ALT, alanineaminotransferase; HR = hazard ratio; CI = confience interval