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Table 2 AUCs, Sensitivities, and Specificities of the DCMC-CRISPR assay, CA-125 ELISA, HE4 ELISA techniques and ROMA index for clinical ovarian cancer diagnosis

From: Dual Cas12a and multiplex crRNA CRISPR strategy ultrasensitive detection novel circRNA biomarker for the diagnosis of ovarian cancer

  

AUC (95% CI)

Cutoff value

Sensitivity %

(95% CI)

Specificity %

(95% CI)

OV versus NC

DCMC-CRISPR (fmol/L)

0.979

 > 17.545

95.5

100

ELISA (CA-125 (U/mL))

0.883

 > 20.70

77.3

96.4

ELISA (HE4 (pmol/L))

0.793

 > 29.40

81.8

67.9

ELISA (ROMA (%))

0.789

 > 2.160

86.4

64.3

  1. CI Confidence interval
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BMC Cancer

ISSN: 1471-2407

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